Use 2D mode. The bot does NOT WORK ON 3D
Enable Double Click to Attack
Enable Start & Stop attack using shortcut bar keys
Make sure you set keybinds properly
Set graphics to low (for better performance)
(Optional) Disable auto change ammo types (Prevents bot using wrong ammo if you run out)
(Optional) Enable retro mode, may give you slightly more FPS, and doesn't affect bot.
DarkOrbit in-game settings example